Experimental rabies vaccines for humans

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development in immunoprophylaxis against rabies for animals and humans

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Novel Vaccines to Human Rabies

Rabies, the most fatal of all infectious diseases, remains a major public health problem in developing countries, claiming the lives of an estimated 55,000 people each year. Most fatal rabies cases, with more than half of them in children, result from dog bites and occur among low-income families in Southeast Asia and Africa. Safe and efficacious vaccines are available to prevent rabies. Howeve...

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Control of rabies: epidemiology of rabies in Asia and development of new-generation vaccines for rabies.

Rabies is an enzootic viral disease widespread throughout the world. Although it is a vaccine-preventable disease, the annual number of human deaths caused by rabies is estimated to be 32,000 in Asia. Phylogenetic analysis based on sequence data of the partial N gene of rabies viruses in Asia has shown that the viruses are divided into five genogroups, distributed in Middle East, South Asia, So...

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Comparative study of antibody titers produced against two BHK rabies vaccines in field trial experimental condition in dogs by RFFIT

Rabies is acutely fatal encephalitis caused by a neurotropic virus. This virus belongs to the family ofRhabdoviridae and genus of Lyssavirus. The virus is almost always transmitted to human through infectedmammalian saliva. Rabies is inoculated to a wound by an infected animal bite. Since infection is establishedin the CNS, the outcome is almost always fatal. According to the outstanding role o...

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Rabies DNA Vaccines: Current Status and Future

Rabies continues to be a significant cause of human and animal mortality, despite the availability of safe and effective prophylactics. Apart from limited access, the cost and complex schedules of rabies biologics often impact on the success of post-exposure prophylaxis in humans in the endemic countries. Mass vaccination of dogs, critical in rabies control, often fails to achieve its goal in r...

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ژورنال

عنوان ژورنال: Expert Review of Vaccines

سال: 2010

ISSN: 1476-0584,1744-8395

DOI: 10.1586/erv.10.105